CORE Immunity^® FAQ's (Frequently Asked Questions)

What is CORE Immunity^®?

In recent times, the world has faced an unprecedented challenge in the form of the COVID-19 pandemic. Whether vaccinated or not, the need for robust immune systems to combat viral threats has never been more apparent. Nutrient Revolution, LLC has responded to this need by introducing CORE Immunity^® - an Immune Health Supplement designed to bolster the body's immune defenses and combat the negative effects of free radical damage.^†

Key Points:

1. Supports Immune System: CORE Immunity^® contains a synergistic blend of essential vitamins (Vitamin C, Vitamin D3) and minerals (Magnesium, Zinc) that are known to support a healthy immune system.

2. Antioxidant Power: Resveratrol, Vitamin C, Coenzyme Q10 (CoQ10) are powerful antioxidants.  They can help neutralize harmful free radicals in the body, reducing oxidative stress and protect against chronic diseases.

3. Respiratory Health: Ingredients like Quercetin, Bromelain, and Black Cumin Seed (Nigella sativa) aid in maintaining respiratory health, making it especially beneficial during cold and flu seasons.

4. Enhanced Absorption: The combination of Quercetin and Citrus Bioflavonoids may improve the absorption of key nutrients, maximizing their effectiveness in supporting your immune system. 

5. Cardiovascular Health: Magnesium and CoQ10 are known to support heart health.  Magnesium can help regulate heart rhythm and CoQ10 can aid in energy production within heart cells. 

6. Energy Production and Cellular Health: CoQ10 and Magnesium also play key roles in the production of ATP, the main energy currency of cells.  This may help support physical performance and overall vitality.

7. Inflammation Reduction: Bromelain, Quercetin and Resveratrol all have anti-inflammatory properties.  They may reduce inflammation and pain in the body and help to manage certain medical conditions.

8. Skin and Eye Health: Vitamin C, Citrus Bioflavonoids and Zinc can contribute to skin and eye health.  Vitamin C is vital for collagen production, Bioflavonoids can protect skin cells from UV damage and Zinc is important for maintaining vision.

COVID-19 has brought to light the critical role of the immune system in combating viral infections. Nutrient Revolution's CORE Immunity^® - Immune Health Supplement offers several potential benefits for those affected by COVID-19, Long COVID (Post-COVID-19), Omicron and other Viral Variant/Subvariant Strains:

1. Quercetin: Quercetin, known for its anti-inflammatory, antioxidant, analgesic properties, and its ability to inhibit the NLRP3 inflammasome, holds promise as a potential therapy for mitigating severe inflammation in COVID-19 patients. Quercetin has also shown promise in inhibiting viral entry into cells, potentially slowing the spread of the virus within the body.^†

2. Quercetin-Vitamin C-Bromelain Combination: Quercetin can be poorly absorbed on its own. However, Bromelain, an enzyme derived from pineapple, can improve the absorption of Quercetin when taken together.  Both Quercetin and Vitamin C are antioxidants, which means they help protect cells from damage caused by free radicals and oxidative stress.  Combining them may enhance their antioxidant effects.^†

3. Quercetin-Zinc Combination: Zinc ionophore drugs, when combined with zinc supplements, have the potential to function as antiviral agents against a variety of RNA viruses, including SARS-CoV-2.  Quercetin, a natural compound, acts as a zinc ionophore by facilitating the intracellular influx of zinc.^†

4. Zinc: A mineral nutrient, Zinc serves as an effective preventive measure and may shorten the duration of SARS-CoV-2 infection.^†

5. Nigella sativa: According to a recent study, supplementing with Nigella sativa was linked to a quicker resolution of symptoms in individuals with mild COVID-19 infection compared to those receiving standard care alone. Additionally, individuals suffering from post-Covid-19 syndrome (long COVID-19, long-haul COVID-19) might consider incorporating black seeds (Nigella sativa) as a complementary treatment alongside symptomatic management and supportive care to mitigate the risk of worsening symptoms.^†

6. Nigella sativa-Vitamin D3 Combination: The results of another study showed a promising therapeutic benefit of the administration of Nigella sativa and Vitamin D3 combination in Covid-19 patients with mild to moderate symptoms.^†

7. Bromelain: A published study showed that Bromelain may have the ability to break down the SARS-CoV-2 spike protein and inhibit SARS-CoV-2 infection.^†

8. Resveratrol: Resveratrol not only functions as an antiviral agent but also has the potential to enhance immune system activity, suppress the release of pro-inflammatory cytokines, and mitigate lung injury by reducing oxidative stress which may help Covid-19 patients.^†

9. Resveratrol - Transresveratrol: In contrast to standard Resveratrol, Transresveratrol exhibits higher bioavailability, making it more readily absorbed and utilized by the body. It can be assimilated up to 30 times faster than its regular counterpart. Consequently, it is the preferred choice for supplementation owing to its increased potency and superior absorption rate.^†

10. Magnesium: Certain micronutrients, such as Magnesium, have demonstrated the capacity to boost immune system support against respiratory infections. Consequently, Magnesium plays a crucial role in bolstering antiviral defense, including individuals with COVID-19.^† 

11. CoQ10: Research has indicated that supplementation significantly expedited the restoration of mitochondrial health in individuals recovering from post-COVID-19 syndrome (long COVID-19, long-haul COVID-19) and shows the significance of monitoring and maintaining sufficient CoQ10 levels in individuals with post-COVID-19 syndrome.^†

Is CORE Immunity® a prescription medication?

No, CORE Immunity^® is not a prescription medication. It is available as a dietary supplement and can be purchased without a prescription. However, it's essential to consult with a licensed healthcare professional before starting any new supplement, especially if you have underlying health conditions or are taking medications.  Do not use this product if you are pregnant or breastfeeding, have a blood clotting disorder or are taking blood-thinning (anticoagulant) medication.  Discontinue use at least 2 weeks prior to undergoing surgery.  Not recommended for persons under the age of 18.

How should I take CORE Immunity®?

As a dietary supplement, the suggested use is 2 capsules in the morning and 2 capsules in the evening with 10-12 fl oz. of water.  However, it's crucial to follow the dosage instructions and warnings provided on the product label or as directed by your licensed healthcare professional.  Do not exceed the recommended dosage.

References:

Saeedi-Boroujeni, A., & Mahmoudian-Sani, M.-R. (2021). Anti-inflammatory potential of Quercetin in COVID-19 treatment. Journal of Inflammation, 18, 3.

Gordon, A. M., & Hardigan, P. C. (2021). A Case-Control Study for the Effectiveness of Oral Zinc in the Prevention and Mitigation of COVID-19. Frontiers in Medicine, 8, 756707.

Said, S. A., Abdulbaset, A., El-Kholy, A. A., Besckales, O., & Sabri, N. A. (2022). The effect of Nigella sativa and vitamin D3 supplementation on the clinical outcome in COVID-19 patients: A randomized controlled clinical trial. Frontiers in Pharmacology, 13, 1011522.

Naina Mohamed Pakkir Maideen, A., Jumale, A. H., Barakat, I. R., & Albasti, A. K. (2023). Potential of Black Seeds (Nigella sativa) in the Management of Long COVID or Post-acute Sequelae of COVID-19 (PASC) and Persistent COVID-19 Symptoms – An Insight. Volume 23, Issue 4. Published on 13 March, 2023. Article ID: e230223213955.

Koshak, A. E., Koshak, E. A., Mobeireek, A. F., Badawi, M. A., Wali, S. O., Malibary, H. M., Atwah, A. F., Alhamdan, M. M., Almalki, R. A., & Madani, T. A. (2021). Nigella sativa for the treatment of COVID-19: An open-label randomized controlled clinical trial. Complementary Therapies in Medicine, 61, 102769.

Sagar, S., Rathinavel, A. K., Lutz, W. E., Struble, L. R., Khurana, S., Schnaubelt, A. T., Mishra, N. K., Guda, C., Palermo, N. Y., Broadhurst, M. J., Hoffmann, T., Bayles, K. W., Reid, S. P. M., Borgstahl, G. E. O., & Radhakrishnan, P. (2021). Bromelain inhibits SARS‐CoV‐2 infection via targeting ACE‐2, TMPRSS2, and spike protein. Clin Transl Med, 11(2), e281. 

van Brummelen, R.,  van Brummelen, A. C. (2022). The potential role of resveratrol as a supportive antiviral in treating conditions such as COVID-19 - A formulator's perspective. Biomedicine  Pharmacotherapy, 148, 11267. Elsevier.

Guerrero-Romero, F., Micke, O., Simental-Mendía, L. E., Rodríguez-Morán, M., Vormann, J., Iotti, S., Banjanin, N., Rosanoff, A., Baniasadi, S., Pourdowlat, G., Nechifor, M., & Ścibior, A. (2023). Importance of Magnesium Status in COVID-19. Biology (Basel), 12(5), 735.

Sumbalová, Z., Kucharská, J., Rausová, Z., Palacka, P., Kovalčíková, E., Takácsová, T., Mojto, V., Navas, P., Lopéz-Lluch, G., & Gvozdjáková, A. (2022). Reduced platelet mitochondrial respiration and oxidative phosphorylation in patients with post COVID-19 syndrome are regenerated after spa rehabilitation and targeted ubiquinol therapy. Frontiers in Molecular Biosciences, 9, 1016352.